Disease or Condition
(click on title for more disease information, causes, prevention measures, etc.) | Additional Information / Resources | CDC Recommended Testing
(click for complete CDC testing recommendations and case definition) | Report Within |
| Acute flaccid myelitis (AFM) | KDPH AFM Quicksheet | MRI | 5 days |
| Anaplasmosis | | Culture, PCR, IFA | 5 days |
| Anthrax | | Culture, PCR, IHC | 24 hours |
Arboviral Diseases, neuroinvasive and non-neuroinvasive:
California serogroup virus diseases:
– California encephalitis virus
– Jamestown Canyon virus
– Keystone virus
– La Crosse virus
– Snowshoe hare virus
– Trivittatus viruses
Chikungunya Virus
Eastern Equine Encephalitis
Powassan Virus
St. Louis Encephalitis
Venezuelan equine encephalitis disease
West Nile Viruses
Western Equine Encephalitis | | Isolation, PCR | 1 day |
| Asbestosis | | | 3 months of diagnosis |
| Babesiosis | | Culture, PCR, NAAT | 5 days |
| Botulism | | Isolation and identification | 24 hours |
| Brucellosis | | Culture and identification, PCR | 1 day |
| Campylobacteriosis | Campylobacter Fact Sheet | Isolation, PCR | 1 day |
| Candida auris | Use EPID 250 and fax to 502-398-2462 | Detection | 24 hours |
| Carbapenem-resistant Acinetobacter | Use EPID 250 and fax to 502-398-2462 | | 24 hours |
| Carbapenem-resistant Enterobacterales | Use EPID 250 and fax to 502-398-2462 | Isolation | 24 hours |
| Carbapenem-resistant Pseudomonas | Use EPID 250 and fax to 502-398-2462 | | 24 hours |
| Carbon Monoxide Poisoning | | COHb level | 1 day |
| Chagas | | Detection, NAAT, IgG | 5 days |
| Chancroid | | Isolation | 5 days |
| Chlamydia | | Detection, Isolation | 5 days |
| Cholera | | Culture | 1 day |
| Coal Worker’s Pneumoconioses | | | 3 months of diagnosis |
| Coccidioidomycosis | | Culture, EIA, Serology | 5 days |
| Creutzfeldt-Jakob Disease (Transmissible Spongiform Encephalopathy (TSE) and other prion diseases) | | WB confirmed protease-resistant PrP | 5 days |
| Cronobacter spp, invasive disease in an infant <12 months of age | | | 24 hours |
| Cryptosporidiosis | KDPH Cryptosporidium Fact Sheet | PCR, EIA, DFA, Microscopy | 1 day |
| Cyclosporiasis | KDPH Cyclospora Fact Sheet | PCR, Microscopy | 1 day |
| Dengue Virus Infections | | Culture, PCR, IHC, or IFA | 1 day |
| Diphtheria | KDPH Diptheria Quicksheet | Isolation and identification | 24 hours |
| E. coli 0157:H7,Shiga toxin positive (STEC) | | Isolation and identification | 24 hours |
| Ehrlichiosis | | Culture, PCR, IFA | 5 days |
| Foodborne / Waterborne Disease Outbreak | | | 1 day |
| Giardiasis | KDPH Giardia Fact Sheet | EIA, DFA, Microscopy | 1 day |
| Gonorrhea | | Isolation, PCR | 5 days |
| Granuloma inguinale | | | 5 days |
| Haemophilus Influenza, Invasive Disease | KDPH Invasive Haemophilis Influenzae Quicksheet | Isolation and identification, PCR | 1 day |
| Hantavirus Infection, Non-Hantavirus Pulmonary Syndrome | | PCR, ELISA, IFA, Western blot | 1 day |
| Hantavirus pulmonary syndrome (HPS) | | Detection | 1 day |
| Hemolytic Uremia Syndrome (HUS), post-diarrheal | | Anemia with microangiopathic on peripheral blood smear AND Renal injury | 1 day |
| Hepatitis A, acute | | IgM, NAAT | 24 hours |
| Hepatitis B, acute | | HBsAg AND IgM antibody | 1 day |
| Hepatitis B, infant or child aged five years or less (includes infants born to Hep B positive mothers at the time of delivery) | Use EPID 394 form | HBsAg AND IgM antibody | 1 day |
| Hepatitis B, perinatal infection | Use EPID 394 form | HBsAg, HBeAg, HBV DNA | 1 day |
| Hepatitis C, acute | | HCV antibody, HCV RNA | 5 days |
| Hepatitis C, infant or child aged five years or less | Use EPID 394 form | HCV antibody, HCV RNA | 5 days |
| Hepatitis C, perinatal infection | Use EPID 394 form | HCV RNA, HCV genotype, HCV antigen | 5 days |
| Histoplasmosis | | Culture, Serology, PCR | 5 days |
| HIV Infection or AIDS diagnosis | Report case by phone 1-866-510-0008 or mail (Do not fax) | | 5 days |
| Influenza – associated outbreaks/mortality | KDPH Influenza Quicksheet | | 1 day |
| Invasive Pneumococcal Disease (IPD) | KDPH IPD Quicksheet | Isolation | 1 day |
| Lead poisoning | | Blood lead concentration of ≥5 µg/dL (0.24 µmol/L) | 5 days |
| Legionellosis | | Culture, IFA, DFA | 1 day |
| Leprosy / Hansen’s Disease | | Detection | 1 day |
| Leptospirosis | | Isolation, PCR | 1 day |
| Listeriosis | Listeria Fact Sheet | Isolation | 1 day |
| Lymphogranuloma venereum | | | 5 days |
| Lyme Disease | | Isolation, NAAT | 5 days |
| Newborns born to Hepatitis C positive mothers at the time of delivery | | | 5 days |
| Norovirus outbreak | KDPH Norovirus Resources | | 1 day |
| Novel influenza A virus infections | KDPH Avian and Novel Influenza Quicksheet | PCR, subtyping | 24 hours |
| Malaria | | RDT | 5 days |
| Measles | KDPH Measles Quicksheet | Isolation, PCR, IgM | 24 hours |
| Melioidosis | | Isolation, DNA, IHA | 24 hours |
| Meningococcal Disease | KDPH Meningococcal Quicksheet | Culture, PCR | 24 hours |
| Middle East Respiratory Syndrome associated Coronavirus (MERS-CoV) disease | | rRT-PCR | 24 hours |
| Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with SARS-CoV-2 Infection | | Detection | 24 hours |
| Mumps | KDPH Mumps Quicksheet | Culture, PCR | 1 day |
| Pertussis | KDPH Pertussis Quicksheet | Isolation, PCR | 1 day |
| Pesticide-related illness, acute | | | 1 day |
| Plague | | Isolation, Serology | 24 hours |
| Poliovirus, Paralytic Poliomyelitis and Nonparalytic Poliovirus Infection | KDPH Polio Quicksheet | Culture, PCR | 24 hours |
| Psittacosis | | Isolation, PCR, CF, MIF, Serology | 1 day |
| Q Fever | | Culture, PCR, IHC, Serology | 1 day |
| Rabies, animal | | Isolation, DFA, dRIT, IHC, RR-PCR | 24 hours |
| Rabies, human | | Isolation, DFA, RNA | 24 hours |
| Rubella | KDPH Rubella Quicksheet | Isolation, PCR, Serology | 24 hours |
| Rubella, congenital syndrome (CRS) | KDPH CRS Quicksheet | Isolation, Detection, PCR, IgM antibody | 1 day |
| Salmonellosis | Salmonella Fact Sheet | Isolation, CIDT | 1 day |
| Severe Acute Respiratory Syndrome-associated Coronavirus (SARS-CoV) | | Isolation, PCR, EIA | 24 hours |
| Severe Acute Respiratory Syndrome-associated Coronavirus 2 (SARS-CoV-2) (The virus that causes COVID-19) | | Isolation, PCR, EIA | 24 hours |
| Shiga toxin-producing E.coli (STEC) | Shiga Toxin Producing E.coli (STEC) Fact Sheet | Isolation | 1 day |
| Shigellosis | KDPH Shigella Fact Sheet | Isolation, PCR | 1 day |
| Silicosis | | Chest radiograph, Lung histopathology | 3 months |
| Smallpox | | CDC Only | 24 hours |
| Spotted Fever Rickettsiosis (Rocky Mountain Spotted Fever) | | Isolation, PCR, IHC, IFA | 5 days |
| Streptococcal disease, invasive Group A | | Isolation | 1 day |
| Streptococcal Toxic Shock Syndrome (STSS) | | Isolation and Clinical diagnosis | 1 day |
| Streptococcus pneumoniae, invasive disease | | Identification, Isolation | 1 day |
| Syphilis – primary, secondary, early latent, or congential | | Microscopy, PCR | 1 day |
| Tetanus | KDPH Tetanus Quicksheet | Clinical diagnosis | 1 day |
| Toxic Shock Syndrome (TSS), other than Streptococcal | | Culture and Clinical diagnosis | 1 day |
| Toxoplasmosis | | PCR, Serology | 5 days |
| Trichinellosis | | Serology | 5 days |
| Tuberculosis | | Isolation, NAAT | 1 day |
| Tularemia | | Isolation, PCR, ELISA, Serology | 24 hours |
| Typhoid/Paratyphoid Fever | | Isolation | 1 day |
| Vancomycin-intermediate Staphylococcus Aureus and Vancomycin-resistant Staphylococcus Aureus (VISA/VRSA) | Use EPID 250 and fax to 502-398-2462 | Isolation | 24 hours |
| Varicella/Chickenpox | KDPH Varicella Quicksheet
KDPH Zoster (Shingles) Quicksheet
| Isolation, PCR, DFA, Serology | 1 day |
| Vibrio (Vibrionaceae spp., other than Vibrio cholerae O1 or O139) | Vibrio Fact Sheet | Isolation | 1 day |
Viral Hemorrhagic Fever (VHF):
Crimean-Congo hemorrhagic fever,
Ebola,
Lassa fever,
Lujo fever,
Marburg,
New World arenaviruses including:
Guanarito virus, Junin virus, Machupo virus, and Sabia virus | | Isolation, PCR, ELISA IHC and Clinical diagnosis | 24 hours |
| Yellow Fever | | Isolation, PCR, Serology | 24 hours |
| Zika Virus Disease | | Detection | 1 day |
